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Selected role

Senior Machine Learning Engineer

Genentech San Francisco, CA, US

$188k - $349k Senior Full-time

THE POSITION

Why Genentech

We’re passionate about delivering on Our Promise to improve the lives of patients and create healthier communities for all. We foster a culture of inclusivity, integrity and creativity while boldly pursuing answers to the world’s most complex health challenges and transforming society.

The Opportunity

Our Data, Analytics, and AI team is dedicated to solving complex healthcare challenges and improving patient outcomes. Data, Analytics, and AI empowers business partners across Commercial, Medical, and Government Affairs (CMG) to make impactful decisions by leveraging data, analytics, business products, and AI/ML to enable fast, targeted actions in rapidly evolving business contexts.

Data, Analytics, and AI fosters a unified understanding of customers, actions, and outcomes by integrating analytics and insights seamlessly into CMG’s evolving digital, data, and automation platforms, creating scalable solutions and eliminating silos.

In Data, Analytics, and AI, you will work as a trusted, objective advisor and expert, recommending critical decisions and actions to be taken with credibility and a focus on driving measurable impact. You will be part of a thriving culture built on collaboration and innovation.

The Senior Machine Learning Engineer sits on the Data Science Team within our Strategic Analytics & Intelligence Organization (SAI) and exists to help the CMG (Commercial, Medical and Government) organization achieve its vision by unlocking value from data quicker and more effectively. As a center of excellence, the Commercial Data Science team leverages advanced data science capabilities, working across CMG to develop strategic and holistic solutions by identifying and leading innovative analytic projects & pilots to enable patient and customer solutions.

The Senior Machine Learning Engineer will bring a robust understanding of machine learning operations (MLOps) to manage and contribute to our machine learning initiatives.

The Senior Machine Learning Engineer will design, enhance, scale, and maintain machine learning solutions from conception to deployment in a production environment.
You will collaborate with data scientists, software engineers, and business stakeholders to translate business requirements into scalable ML systems.
You will also architect and uphold MLOps pipelines using job scheduling frameworks to streamline data preparation, training, deployment, and machine learning model lifecycles.
In addition to ensuring best practices in code quality, version control, and CI/CD for machine learning pipelines, you will also design and implement robust monitoring systems for deployed models to track performance, data drift, and anomalies.
The MLOps Engineer will also pioneer and administer model retraining, A/B testing, and progressive deployment strategies for continuous model enhancement.
You will contribute to the company's machine learning architecture to support scalable and repeatable model training and deployment.
Facilitate the creation of automated processes for model validation and testing.

WHO YOU ARE

You hold a Bachelor’s Degree in Computer Science or related technical discipline and 7+ years of experience working in a machine learning engineer role, with a minimum of 2 years in an MLOps-focused position.
Your expertise in ML frameworks (e.g., TensorFlow, PyTorch), programming languages (e.g., Python, Scala, Java), MLOps technologies (e.g., Kubeflow, MLflow, AWS Sagemaker), and job scheduling frameworks (e.g., Apache Airflow,AWS Step Functions) is strong.
You have a solid understanding and experience with cloud services and containerization technologies/platforms, particularly AWS and Kubernetes.
Proficient with software engineering best practices, including agile development, code reviews, SCM, build processes, testing, and operations.
Experience with distributed computing and big data technologies (e.g., Hadoop, Spark).

Preferred

You have a Masters Degree in Computer Science or related discipline
Experience building and optimizing structured and unstructured big data pipelines, architectures, and datasets.
Excellent communication skills to effectively collaborate with cross-functional teams.

The expected salary range for this position based on the primary location of CA is $188,200 - $349,400. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

JOB FACTS

Job Sub Category

Artificial Intelligence & Machine Learning

Schedule

Full time

Job Type

Regular

Posted Date

Mar 5th 2026

Job ID

202602-104585

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